糖心视频

Director, of the Michael Szwarc Polymer Research Institute & Professor

Department of Chemistry
218 Jahn Lab

igivanov@esf.edu
315-470-6860

Education

• Ph.D. – 1986, Polymer Chemistry, , BAS, Sofia;
• M.S. – 1979, Organic Chemistry, , Sofia (Bulgaria);

Employment

•  
• 2016-present, Professor, Department of Chemistry 糖心视频
• 2015-present, Director, The Michael M. Szwarc Polymer Research Institute 糖心视频
• 2015-2018, Chair, Department of Chemistry 糖心视频
• 1996-2015, Associate Professor, Department of Chemistry 糖心视频
• 1996-2000, Visiting Assistant Professor, Department of Chemistry and Chemical Biology .
• 1990-1996, Visiting Scientist, Research Associate and Manager of the Polymer Characterization Facility, Cornell University and ;
• 1987-1993, Research Associate, Senior Research Associate, R&D Institute for Special Chemicals, Sofia;
• 1979-1986, Chemist and Research Associate, , BAS, Sofia;

Service for Scientific Journals

MDPI Molecules, Macromolecular Chemistry: Associate Editor-in-Chief: 

Frontiers in Soft Matter, Associate Editor Polymers: 

MDPI Polymers, Editorial Board Member: 

Michael M. Szwarc Polymer Research Institute

Honors

• 2023-present, Cortesy Associate Professor, Department of Biomedical and Chemical Engineering, Syracuse University
• 2021-2022: Fulbright Scholar, http://www.fulbright.pt/fulbrighters/u-s-grantees/academic-year-2021-2022/ivan-gitsov-ivanov/
• 2017: SUNY Chancellor's Award for Excellence in Scholarship and Creative Activities
• 2011, 2013: University Guest Professor, ETH-Zürich, Switzerland, 
• 2011: External Honorary Member, Polymer Chemistry Group, ETH-Zürich, Switzerland,  
• 2010: Guest Professor, , Zaragoza, Spain
• 1999: Cottrell Scholar ();
• 1990: Greve Foundation Fellow (William & Mary Greve Foundation);

Research

   The research focus of our group is aimed at the design, synthesis and evaluation of novel polymers and copolymers with unique architecture, composition and properties that can be used for advanced applications. The synthetic projects involve extensive use of various methods for organic functional group (trans)formation, polycondensation techniques and multiple procedures for controlled or "living" chain-growth polymerization. State-of-the-art methods are used for isolation, identification and characterization of the macromolecules formed including size-exclusion chromatography with multiple detection, FT-IR, UV-Vis, Fluorescence and NMR spectroscopies, MALDI-TOF spectrometry and microscopy. The biological activity and biocompatibility of selected materials are evaluated in collaboration with other research groups and laboratories in USA and Europe. The combination of these methods places our research at the interfaces of organic chemistry, polymer science, biotechnology and molecular medicine (see a recent news reports on our activities in this area   and

   Our efforts are almost equally divided between the creation of novel macromolecular architectures (linear-dendritic copolymers and hydrogels, hyperbranched macromolecules and linear-hyperbranched copolymers) and the evaluation of these materials for novel biomedical applications (polymeric prodrugs, systems for covalent or passive drug binding and sustained delivery) and for new biotechnological uses (formation of unique semi-artificial enzymes through site-specific nano-contacts and no chemical / genetic modification of the proteins).

   A leading motif throughout our research is the development and use of “green” and sustainable chemistry practices.

Thanks to the hard work and devotion of our students our research was ranked among the top 2% of most cited worldwide (among the top 1 % in polymers):

Novel Polymers

Solvent-free synthesis of biostable segmented polyurethane shape memory polymers for biomedical applications. J. Mater. Chem. B 12, 1217-1231 (2024); M. Ramezani, D. Getya, I. Gitsov, M.B.B. Monroe* 

Polymerization Initiated by Graphite Intercalation Compounds Revisited: One-Pot Synthesis of Amphiphilic Pentablock Copolymers. Macromol 2(2), 184-193 (2022); N.G. Vladimirov, I. Gitsov* 

Nonionic Amphiphilic Linear Dendritic Copolymers. Morphology Tuning by Solvent-Induced Self-Assembly. Macromolecules 52(15), 5563-5573 (2019); X. Liu, I. Gitsov* 

Thermosensitive Amphiphilic Janus Dendrimers with Embedded Metal Binding Sites. Synthesis and Self-Assembly. Macromolecules 51(14), 5085-5100 (2018); X. Liu, I. Gitsov*  

Synthesis and Characterization of Novel Amphiphilic Super-H Copolymers with Linear-Dendritic Architecture. J. Polym. Sci., Part A: Polym. Chem. 53(2), 178-182 (2015); I. Gitsov,* I.V. Berlinova, N.G. Vladimirov 

 “Click” Synthesis of Intrinsically Hydrophilic Dendrons and Dendrimers Containing Metal Binding Moieties at Each Branching Unit. Macromolecules 47(6), 2199-2213 (2014); L. Wang, D.J. Kiemle, C.J. Boyle, E.L. Connors, I. Gitsov* 

. J. Polym. Sci., Part A: Polym. Chem. 46(16), 5295-5314 (2008) I. Gitsov

Hydrogels

Composite Hydrogels Based on Poly(Ethylene Glycol) and Cellulose Macromonomers as Fortified Materials for Environmental Cleanup and Clean Water Safeguarding. Int. J. Mol. Sci. 24(8), 7558 (2023); D. Getya, A. Lucas, I. Gitsov* 

Synthesis and Characterization of Zwitterionic Polymer Brush Functionalized Hydrogels with Ionic Responsive Coefficient of Friction. Langmuir 36(14), 3932-3940 (2020); A. O. Osaheni, A. A. Shakoor, I. Gitsov, P. T. Mather, M. M. Blum* 

Preparation and Characterization of Novel Amphiphilic Hydrogels with Covalently Attached Drugs and Fluorescent Markers, Macromolecules 43(23), 10017-10030 (2010); C. Lin, I. Gitsov* 

. J. Polym. Sci., Part A: Polym. Chem. 43(18), 4017-4029 (2005) C. Zhu, C. Hard, C. Lin, I. Gitsov

 .J. Am. Chem. Soc. 125(37), 11228-11234 (2003) I. Gitsov, C. Zhu

35(22), 8418-8427 (2002) I. Gitsov, C. Zhu

Materials for Biomedical Applications

Hydroxyapatite-poly(D,L-lactide) Nanografts. Synthesis and Characterization as Bone Cement Additives. Molecules 26, 424 (2021); K.L. Goranova, A.K. Kattenhøj Sloth Overgaard, I. Gitsov* 

A Single Enzyme Mediates the “Quasi-Living” Formation of Multiblock Copolymers with a Broad Biomedical Potential. Biomacromolecules 21(6), 2132-2146 (2020); D.M. Scheibel, D. Guo, J. Luo, I. Gitsov* 

. J. Polym. Sci., Part A: Polym. Chem. 46(12), 4130-4139 (2008) I. Gitsov, F.E. Johnson

Immobilization of Aminothiols on Poly(oxyethylene H-phosphonates) and Poly(oxyethylene phosphate)s – an Approach to Polymeric Protective Agents for Radiotherapy of Cancer. J. Polym. Sci., Part A: Polym. Chem. 45(7), 1349-1363 (2007) K. Troev*, I. Tsatcheva, N. Koseva, R. Georgieva, I. Gitsov* 

J. Med. Chem. 45(26), 5797-5801 (2002) R. Georgieva, R. Tsevi, K. Kossev, R. Kusheva, M. Balgjiska, R. Petrova, V. Tenchova, I. Gitsov*, K. Troev* 

Dendritic-polymer drug delivery structures characterized by a novel triple detection method. Drug Disc. Today 6(2), 108-109 (2001) I. Gitsov*, P. Clarke 

Biocatalysis

Enzymes in “Green” Synthetic Chemistry: Laccase and Lipase. Molecules 29, 989 (2024); D.M. Scheibel, I.P.I. Gitsov, I. Gitsov*  

Enzymatic synthesis and antimicrobial activity of oligomer analogues of medicinal biopolymers from comfrey and other species of Boraginaceae family. Pharmaceutics 14(1), 115 (2022); M. Merlani, D. Scheibel, V. Barbakadze, L. Gogilashvili, L. Amiranashvili, A. Geronikaki, V. Catania, D. Schillaci, G. Gallo, I. Gitsov* 

Novel Amphiphilic Dendronized Copolymers Formed by Enzyme-Mediated “Green” Polymerization. Biomacromolecules 22(4), 1706-1720 (2021); X. Liu, L. Wang, I. Gitsov* 

Polymer-Assisted Biocatalysis: Polyamide 4 Microparticles as Promising Carriers of Enzymatic Function. Catalysts 10, 767 (2020); N. Dencheva, J. Braz, D. Scheibel, M. Malfois, Z. Denchev,* I. Gitsov*  

Unprecedented Enzymatic Synthesis of Perfectly Structured Alternating Copolymers via “Green” Reaction Cocatalyzed by Laccase and Lipase Compartmentalized Within Supramolecular Complexes. Biomacromolecules, 20(2), 927-936 (2019); D.M. Scheibel, I. Gitsov* 

Polymer-Assisted Biocatalysis: Unprecedented Enzymatic Oxidation of Fullerene in Aqueous Medium. J. Polym. Sci., Part A: Polym. Chem. 50(1), 119-126 (2012); I. Gitsov,* A. Simonyan, L. Wang, A. Krastanov, S.W. Tanenbaum, D. Kiemle 

. 1. Formation and Catalytic Activity of Supramolecular Complexes of Laccase and Linear Dendritic Block Copolymers. Biomacromolecules 9(3), 804-811 (2008); I. Gitsov, J. Hamzik, J. Ryan, A. Simonyan, J. P. Nakas, Sh. Omori, A. Krastanov, T. Cohen, S.W. Tanenbaum

Smart Polymer Recycling (partially with Prof. K. Troev)

Conversion and Removal Strategies for Microplastics in Wastewater Treatment Plants and Landfills. Chem. Eng. J. 406, 126715 (2021); L. Hou, D. Kumar, C.G. Yoo, I. Gitsov, E.L.W. Majumder* 

. J. Appl. Polym. Sci. 105(2), 302-308 (2007) K. Troev*, G. Grancharov, V. Mitova, St. Shenkov, A. Topliyska, Ivan Gitsov*

. 91(4), 778-788 (2006) K. Troev*, N. Todorova, V. Mitova, St. Vassileva, I. Gitsov*

. J. Appl. Pol. Sci. 90(4), 1148-1152 (2003) K. Troev*, G. Grancharov, R. Tsevi, I. Gitsov*

42(1), 39-42 (2001) K. Troev*, R. Tsevi, I. Gitsov*

Full List of Publications

• Full List